Novel way to diagnose Alzheimer’s disease by blood analysis

Novel way to diagnose Alzheimer’s disease by blood analysis

Novel way to diagnose Alzheimer’s disease by blood analysis

Using proteomics and other advanced tools of molecular biology, an international team of researchers led by a group from Karolinska Institutet have found a novel way to diagnose Alzheimer’s disease by blood analysis, with a potential to uncover the underlying cause of the disease and prevent its development.

When we age, so do proteins in our body, including long-lived proteins in our blood, such as albumin. One of the major manifestations of protein aging is the loss of ammonia, known as deamidation. As deamidation products accumulate, the protein molecule loses its structure, function and solubility, and starts aggregating.

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